HOW ALLERGIES ATTACK.
Allergies are the result of an over-reactive immune system.1 When allergies occur, the immune system mistakenly identifies an allergen (pollen, pet dander, mold, and dust mites) as an “invader.”3 In response, the body mounts an inappropriate immune response—similar to one that it would launch against something much more harmful, such as the cold virus.5
To rid itself of the “invader,” the immune response triggers a response that results in you experiencing symptoms—such as sneezing, runny nose, and itchy, watery eyes.2
The diagram below takes you through the stages of a typical allergy attack, starting from the allergens entering your nose, to showing how your immune system responds, and the resulting symptoms.

ALLERGIES ARE GETTING WORSE. CLIMATE CHANGE MAY BE A FACTOR.
Today, 50 million Americans suffer from nasal allergies.9 Studies say that climate change may be to blame. With plants producing more pollen per year, sending more allergens into the air we breathe, our immune systems are working overtime.10,11
Sources:
- Wallace DV, Dykewicz MS, Bernstein DI, Blessing-Moore J, Cox L, Khan DA, et al. The diagnosis and management of rhinitis: an updated practice parameter. J Allergy Clin Immunol. 2008 Aug:122(2). [PubMed]
- Bousquet J, Schünemann HJ, Samolinski B, et al. Allergic Rhinitis and its Impact on Asthma (ARIA): achievements in 10 years and future needs. J Allergy Clin Immunol. 2012;130(5):1049-62.
- Glossary of HIV/AIDS-Related Terms. AIDSinfo website.
http://aidsinfo.nih.gov/contentfiles/GlossaryHIVrelatedTerms_English.pdf Published 2011. Accessed March 2014. - Angel C, Chen C, Horlacher O, et al. Distinctive localization of antigen-presenting cells in human lymph nodes. Blood. 2009; 113 (6): 1257-1267.
- Bell, E. T-cell-APC interactions. Nat Rev Immunol. 2004; 4 (12): 930.
- Alberts B, Johnson A, Lewis J, et al. Helper T Cells and Lymphocyte Activation. In: Molecular Biology of the Cell. 4th ed. New York, NY: Garland Science; 2002.
- Stone KD, Prussin C, Metcalfe DD. IgE, mast cells, basophils, and eosinophils. J Allergy Clin Immunol. 2010; 125 (2): 73-80.
- Allergic Reactions. MedlinePlus website. http://www.nlm.nih.gov/medlineplus/ency/article/000005.htm Published 2012. Accessed March 2014.
- Allergy Facts. ACAAI website.
http://acaai.org/news/facts-statistics/allergies. Accessed August 2015. - National Wildlife Federation Extreme allergies and global warming.
http://www.nwf.org/pdf/reports/NWF_AllergiesFinal.pdf
Accessed April 25.2014 - Root TL Price JT Hall KR. Schneider SH Rosenzweig C. Pounds JA
Fingerprints of global warming on wild animals and plants Nauture.
2003 421(6918):57-60
HOW ALLERGIES ATTACK
Allergies are the result of an over-reactive immune system.1 When allergies occur, the immune system mistakenly identifies an allergen (pollen, pet dander, mold, and dust mites) as an “invader.”3 In response, the body mounts an inappropriate immune response—similar to one that it would launch against something much more harmful, such as the cold virus.5
To rid itself of the “invader,” the immune response triggers a response that results in you experiencing symptoms—such as sneezing, runny nose, and itchy, watery eyes.2
The diagram below takes you through the stages of a typical allergy attack, starting from the allergens entering your nose, to showing how your immune system responds, and the resulting symptoms.

ALLERGIES ARE GETTING WORSE. CLIMATE CHANGE MAY BE A FACTOR.
Today, 50 million Americans suffer from nasal allergies.9 Studies say that climate change may be to blame. With plants producing more pollen per year, sending more allergens into the air we breathe, our immune systems are working overtime.10,11
Sources:
1. Wallace DV, Dykewicz MS, Bernstein DI, Blessing-Moore J, Cox L, Khan DA, et al. The diagnosis and management of rhinitis: an updated practice parameter. J Allergy Clin Immunol. 2008 Aug:122(2). [PubMed]
2. Bousquet J, Schünemann HJ, Samolinski B, et al. Allergic Rhinitis and its Impact on Asthma (ARIA): achievements in 10 years and future needs. J Allergy Clin Immunol. 2012;130(5):1049-62.
3. Glossary of HIV/AIDS-Related Terms. AIDSinfo website.
http://aidsinfo.nih.gov/contentfiles/GlossaryHIVrelated
Terms_English.pdf Published 2011. Accessed March 2014.
4. Angel C, Chen C, Horlacher O, et al. Distinctive localization of antigen-presenting cells in human lymph nodes. Blood. 2009; 113 (6): 1257-1267.
5. Bell, E. T-cell-APC interactions. Nat Rev Immunol. 2004; 4 (12): 930.
6. Alberts B, Johnson A, Lewis J, et al. Helper T Cells and Lymphocyte Activation. In: Molecular Biology of the Cell. 4th ed. New York, NY: Garland Science; 2002.
7. Stone KD, Prussin C, Metcalfe DD. IgE, mast cells, basophils, and eosinophils. J Allergy Clin Immunol. 2010; 125 (2): 73-80.
8. Allergic Reactions. MedlinePlus website. http://www.nlm.nih.gov/medlineplus/ency/article/000005.htm Published 2012. Accessed March 2014.
9. Allergy Facts. ACAAI website.
http://acaai.org/news/facts-statistics/allergies. Accessed August 2015.
10. National Wildlife Federation Extreme allergies and global warming.
http://www.nwf.org/pdf/reports/NWF_AllergiesFinal.pdf. Accessed April 25.2014
11. Root TL Price JT Hall KR. Schneider SH Rosenzweig C. Pounds JA Fingerprints of global warming on wild animals and plants Nauture. 2003 421(6918):57-60